Startup

Aptadir Therapeutics

Preclinical biotech developing RNA medicines that reprogram DNA methylation to reactivate silenced genes

  • Biotech & Life Sciences
  • Milan, Italia
  • Semilla

Sobre Aptadir Therapeutics

Aptadir Therapeutics is a Milan-based preclinical biotech developing RNA medicines that reprogram DNA methylation. Its platform builds on research by co-founder Annalisa Di Ruscio showing that specific RNAs bind and inhibit the enzyme DNMT1. Using DNMT-interacting RNAs (DiRs), it aims to reactivate silenced genes either globally or at a chosen gene locus. Launched in 2024 as the first company created by Italy's EXTEND tech-transfer hub, it targets genetic diseases such as Fragile X syndrome and hard-to-treat cancers.

Aptadir Therapeutics logo
Sector
Biotech & Life Sciences
Sede
Milan, Italia
Fase
Semilla

Rondas de financiación

FechaRondaImporteInversores principales
Semilla40,0 M €4BIO Capital
PresemillaNo reveladoEXTEND (Italian National Technology Transfer Hub for biopharma)