Startup

Aptadir Therapeutics

Preclinical biotech developing RNA medicines that reprogram DNA methylation to reactivate silenced genes

  • Biotech & Life Sciences
  • Milan, Italia
  • Seed

Chi è Aptadir Therapeutics

Aptadir Therapeutics is a Milan-based preclinical biotech developing RNA medicines that reprogram DNA methylation. Its platform builds on research by co-founder Annalisa Di Ruscio showing that specific RNAs bind and inhibit the enzyme DNMT1. Using DNMT-interacting RNAs (DiRs), it aims to reactivate silenced genes either globally or at a chosen gene locus. Launched in 2024 as the first company created by Italy's EXTEND tech-transfer hub, it targets genetic diseases such as Fragile X syndrome and hard-to-treat cancers.

Aptadir Therapeutics logo
Settore
Biotech & Life Sciences
Sede
Milan, Italia
Fase
Seed

Round di finanziamento

DataRoundImportoInvestitori principali
Seed40,0 Mln €4BIO Capital
Pre-seedNon divulgatoEXTEND (Italian National Technology Transfer Hub for biopharma)